Rosh Psychiatry Board Practice Exam

Which antipsychotic medication is approved for use in adolescents diagnosed with autism?

1. Haloperidol

2. Pimozide

3. Risperidone

4. Thioridazine

The correct answer is: Risperidone

Risperidone is the antipsychotic medication that has been specifically approved for use in adolescents diagnosed with autism. This approval is based on its efficacy in managing symptoms associated with autism such as irritability, aggression, and mood swings. Risperidone has been shown to help reduce disruptive behavior and improve overall functioning in children and adolescents with autism spectrum disorder. The clinical use of risperidone in this population is supported by various studies that demonstrate its ability to improve behavioral symptoms while being relatively well-tolerated. Its pharmacological profile makes it suitable for managing the complex behavioral challenges that often accompany autism. In contrast, while haloperidol and pimozide are medications that have been used in the past for similar issues, they are not specifically approved for this indication based on recent guidelines and evidence. Thioridazine, though historically significant, is generally considered in antiquated practices due to its unfavorable side effect profile, particularly in young patients. Hence, risperidone stands out as the appropriate choice for treating adolescents with autism in the current treatment landscape.