Rosh Psychiatry Board Practice Exam

What is the first-line treatment for a patient showing symptoms of intoxication with PCP?

1. Neuroleptics

2. Opioid antagonists

3. Benzodiazepines

4. Sodium bicarbonate

The correct answer is: Benzodiazepines

The first-line treatment for a patient exhibiting symptoms of intoxication with PCP (phencyclidine) is the administration of benzodiazepines. PCP intoxication can lead to various symptoms, including agitation, hallucinations, and violent behavior. Benzodiazepines are effective because they have calming and sedative effects, which can help manage agitation and anxiety associated with PCP overdose. In cases of severe agitation and violent behavior, benzodiazepines can also aid in preventing further injury to both the patient and the healthcare staff. They help reduce autonomic overactivity and provide a safer environment for both the patient and those around them. While other treatments may be considered, benzodiazepines are primarily utilized for their ability to effectively mitigate the acute psychological and behavioral effects of PCP intoxication. Other options, such as neuroleptics, may be used in certain situations for severe agitation, but they carry risks, such as potentially worsening the symptoms or causing movement disorders. Opioid antagonists and sodium bicarbonate are not standard treatments for PCP intoxication, as they do not address the specific symptoms associated with this substance. Thus, benzodiazepines remain the most appropriate initial choice for addressing PCP intoxication symptoms.